Alonso, Jose M

Plant and Microbial Biology
jmalonso@ncsu.edu
919-515-5729
919-515-3355 fax
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My research focuses on uncovering the molecular mechanisms that underlie ethylene signaling and response in Arabidopsis. By employing a combination of classical molecular genetic, genomic, and cell biology approaches, I am elucidating the ethylene signal transduction cascade, as well as the net of interactions between this pathway and other hormonal and developmental signals. Recently, my colleagues and I have found that some of the tissue specificity observed in response to ethylene is due to the local activation of auxin biosynthesis. These findings have opened a new avenue in the study of auxin production in plants and have provided new tools for investigating the role of auxin biosynthesis in ethylene response and plant development in general. My lab is also committed to generating new genetic tools that will facilitate and accelerate gene-function characterization. Towards this goal, I am implementing a new recombineering approach that will enable large-scale gene tagging in Arabidopsis, preserving the chromosomal environment of the tagged genes.

 
Expertise:
  Plant Genomics and Genetics | Molecular Biology | Plant Physiology
Country(s) of experience:
  Austria | China-Peoples Rep | Germany | Sweden
Type(s) of International Experience:
  Speaker at an international conference | Other international activities | Advisor for international students | Host for international faculty | Host for international post-doc
Language(s):
  Catalan | Spanish
Projects:
  A Small-Molecule Screen Identifies L-Kynurenine That Competitively Inhibits TAA1/TAR Activity in Ethylene-Directed Auxin Biosynthesis and Root Growth
01/01/2010 - 12/31/2013
Funding Agency/Sponsor:
Institutional Partner:
  The Arabidopsis YUCCA1 flavin monooxygenase functions in the indole-3-pyruvic acid branch of auxin biosynthesis
01/01/2010 - 12/31/2010
Funding Agency/Sponsor:
Institutional Partner: Umeå Plant Science Centre (UPSC), Sweden
  Local auxin sources orient apical-basal axis in Arabidopsis embryos
01/01/2010 - 12/31/2010
Funding Agency/Sponsor:
Institutional Partner: Institute of Science and Technology Austria (IST)
  Arabidopsis SABRE and CLASP interact to stabilize cell division plane orientation and planar polarity
01/01/2010 - 12/31/2010
Funding Agency/Sponsor:
Institutional Partner: Umeå Plant Science Centre (UPSC), Sweden
  Kinetic analysis of Arabidopsis glucosyltransferase UGT74B1 illustrates a general mechanism by which enzymes can escape product inhibition
01/01/2010 - 12/31/2010
Funding Agency/Sponsor:
Institutional Partner: Leibniz Institute of Plant Biochemistry, Germany