At the SBR, we measure ourselves by how our services help researchers at NC State and the greater community to do great science. If our services have contributed to a publication of yours, please let us know and we will add you to our growing list of user publications. Please see here for information on how to cite us in the future.

2017  2016

2015

2014

2013

2012

2011

2010

2009

2008

 

2017

 

2016

Joseph J. Maciag, Sarah H. Mackenzie, Matthew B. Tucker, Joshua L. Schipper, Paul Swartz and A. Clay Clark (2016).  A Tunable Allosteric Library of Caspase-3 Identifies Coupling Between Conserved Water Molecules and Conformational Selection.  PNAS Early Publication: (http://www.pnas.org/content/early/2016/09/27/1603549113)

Matthew B. Tucker, Sarah H. MacKenzie, Joseph J. Maciag, Hayley Dirscherl, Paul Swartz, Jeffrey A. Yoder, Paul T. Hamilton3, and A. Clay Clark (2016).  Phage Display and Structural Studies Reveal Plasticity in Substrate Specificity of Caspase-3 from Zebrafish. Protein Science http://onlinelibrary.wiley.com/doi/10.1002/pro.3032/abstract

William B. O’Dell, Paul D. Swartz, Flora Meilleur (2016).  High resolution X-ray and neutron protein crystallography of a fungal lytic polysaccharide monooxygenase expressed from a glyco-engineered Pichia pastoris host.  Acta Crystallographica Section F.  Submitted.

2015

Fetics SK, Guterres H, Kearney BM, Buhrman G, Ma B, Nussinov R, Mattos C. Allosteric effects of the oncogenic RasQ61L mutant on Raf-RBD. Structure. 2015 Mar 3;23(3):505-16. doi: 10.1016/j.str.2014.12.017. Epub 2015 Feb 12. PubMed PMID: 25684575.

Wang D, Coco MW, Rose RB. Interactions with the bifunctional interface of the transcriptional coactivator DCoH1 are kinetically regulated. J Biol Chem. 2015Feb 13;290(7):4319-29. doi: 10.1074/jbc.M114.616870. Epub 2014 Dec 23. PubMedPMID: 25538247; PubMed Central PMCID: PMC4326839.

2014

Kearney BM, Johnson CW, Roberts DM, Swartz P, Mattos C. DRoP: a water analysis program identifies Ras-GTP-specific pathway of communication between membrane-interacting regions and the active site. J Mol Biol. 2014 Feb 6;426(3):611-29. doi: 10.1016/j.jmb.2013.10.036. Epub 2013 Nov 2. PubMed PMID:24189050.

Bodenheimer AM, Cuneo MJ, Swartz PD, He J, O'Neill HM, Myles DA, Evans BR, Meilleur F. Crystallization and preliminary X-ray diffraction analysis of Hypocrea jecorina Cel7A in two new crystal forms. Acta Crystallogr F Struct Biol Commun. 2014 Jun;70(Pt 6):773-6. doi: 10.1107/S2053230X14008851. Epub 2014 May 10. PubMed PMID: 24915091.

Cade C, Swartz P, MacKenzie SH, Clark AC. Modifying caspase-3 activity by altering allosteric networks. Biochemistry. 2014 Dec 9;53(48):7582-95. doi:10.1021/bi500874k. Epub 2014 Nov 21. PubMed PMID: 25343534; PubMed Central PMCID:PMC4263430.

2013

Jiang S, Wright I, Swartz P, Franzen S. The role of T56 in controlling the flexibility of the distal histidine in dehaloperoxidase-hemoglobin from Amphitrite ornata. Biochim Biophys Acta. 2013 Oct;1834(10):2020-9. doi: 10.1016/j.bbapap.2013.06.005. Epub 2013 Jun 20. PubMed PMID: 23792762.

Plummer A, Thompson MK, Franzen S. Role of polarity of the distal pocket in the control of inhibitor binding in dehaloperoxidase-hemoglobin. Biochemistry. 2013 Apr 2;52(13):2218-27. doi: 10.1021/bi301509r. Epub 2013 Mar 22. PubMed PMID: 23480794.

Zhao J, de Serrano V, Zhao J, Le P, Franzen S. Structural and kinetic study of an internal substrate binding site in dehaloperoxidase-hemoglobin A from Amphitrite ornata. Biochemistry. 2013 Apr 9;52(14):2427-39. doi: 10.1021/bi301307f. Epub 2013 Mar 26. PubMed PMID: 23480178.

MacKenzie SH, Schipper JL, England EJ, Thomas ME 3rd, Blackburn K, Swartz P, Clark AC. Lengthening the intersubunit linker of procaspase 3 leads to constitutive activation. Biochemistry. 2013 Sep 10;52(36):6219-31. doi: 10.1021/bi400793s. Epub 2013 Aug 27. PubMed PMID: 23941397.

2012

Walters J, Schipper JL, Swartz P, Mattos C, Clark AC. Allosteric modulation of caspase 3 through mutagenesis. Biosci Rep. 2012 Aug;32(4):401-11. doi: 10.1042/BSR20120037. PubMed PMID: 22607239; PubMed Central PMCID: PMC3392103.

Holzapfel G, Buhrman G, Mattos C. Shift in the equilibrium between on and off states of the allosteric switch in Ras-GppNHp affected by small molecules and bulk solvent composition. Biochemistry. 2012 Aug 7;51(31):6114-26. Epub 2012 Jul 30. PubMed PMID: 22845804.

Lu X, Guanga GP, Wan C, Rose RB. A novel DNA binding mechanism for maf basic region-leucine zipper factors inferred from a MafA-DNA complex structure and binding specificities. Biochemistry. 2012 Dec 4;51(48):9706-17. doi: 10.1021/bi301248j. Epub 2012 Nov 20. PubMed PMID: 23148532.

de Serrano V, Franzen S. Structural evidence for stabilization of inhibitor binding by a protein cavity in the dehaloperoxidase-hemoglobin from Amphitrite ornata. Biopolymers. 2012;98(1):27-35. doi: 10.1002/bip.21674. Epub 2011 May 17. PubMed PMID: 23325557.

Gagnon KT, Biswas S, Zhang X, Brown BA 2nd, Wollenzien P, Mattos C, Maxwell ES. Structurally conserved Nop56/58 N-terminal domain facilitates archaeal box C/D ribonucleoprotein-guided methyltransferase activity. J Biol Chem. 2012 Jun 1;287(23):19418-28. doi: 10.1074/jbc.M111.323253. Epub 2012 Apr 11. PubMed PMID: 22496443; PubMed Central PMCID: PMC3365980.

2011

Buhrman G, O'Connor C, Zerbe B, Kearney BM, Napoleon R, Kovrigina EA, Vajda S, Kozakov D, Kovrigin EL, Mattos C. Analysis of binding site hot spots on the surface of Ras GTPase. J Mol Biol. 2011 Nov 4;413(4):773-89. doi: 10.1016/j.jmb.2011.09.011. Epub 2011 Sep 16. PubMed PMID: 21945529; PubMed Central PMCID: PMC3247908.

Biswas S, Buhrman G, Gagnon K, Mattos C, Brown BA 2nd, Maxwell ES. Comparative analysis of the 15.5kD box C/D snoRNP core protein in the primitive eukaryote Giardia lamblia reveals unique structural and functional features. Biochemistry. 2011 Apr 12;50(14):2907-18. doi: 10.1021/bi1020474. Epub 2011 Mar 18. PubMed PMID: 21366326.

Buhrman G, Kumar VS, Cirit M, Haugh JM, Mattos C. Allosteric modulation of Ras-GTP is linked to signal transduction through RAF kinase. J Biol Chem. 2011 Feb 4;286(5):3323-31. doi: 10.1074/jbc.M110.193854. Epub 2010 Nov 22. PubMed PMID: 21098031; PubMed Central PMCID: PMC3030338.

2010

Martin SL, Guenther RH, Sit TL, Swartz PD, Meilleur F, Lommel SA, Rose RB. Crystallization and preliminary X-ray diffraction analysis of red clover necrotic mosaic virus. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Nov 1;66(Pt 11):1458-62. doi: 10.1107/S1744309110032483. Epub 2010 Oct 28. PubMed PMID: 21045294; PubMed Central PMCID: PMC3001647.

Walters J, Swartz P, Mattos C, Clark AC. Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3. Arch Biochem Biophys. 2011 Apr 1;508(1):31-8. doi: 10.1016/j.abb.2011.01.011. Epub 2011 Jan 23. PubMed PMID: 21266160; PubMed Central PMCID: PMC3070916.

Buhrman G, Holzapfel G, Fetics S, Mattos C. Allosteric modulation of Ras positions Q61 for a direct role in catalysis. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):4931-6. doi: 10.1073/pnas.0912226107. Epub 2010 Mar 1. PubMed PMID: 20194776; PubMed Central PMCID: PMC2841912.

de Serrano VS, Davis MF, Gaff JF, Zhang Q, Chen Z, D'Antonio EL, Bowden EF, Rose R, Franzen S. X-ray structure of the metcyano form of dehaloperoxidase from Amphitrite ornata: evidence for photoreductive dissociation of the iron-cyanide bond. Acta Crystallogr D Biol Crystallogr. 2010 Jul;66(Pt 7):770-82. doi: 10.1107/S0907444910014605. Epub 2010 Jun 19. PubMed PMID: 20606257.

de Serrano V, D'Antonio J, Franzen S, Ghiladi RA. Structure of dehaloperoxidase B at 1.58 A resolution and structural characterization of the AB dimer from Amphitrite ornata. Acta Crystallogr D Biol Crystallogr. 2010 May;66(Pt 5):529-38. doi: 10.1107/S0907444910004580. Epub 2010 Apr 21. PubMed PMID: 20445228; PubMed Central PMCID: PMC2865366.

Rho H, Jones CN, Rose RB. Kinetic stability may determine the interaction dynamics of the bifunctional protein DCoH1, the dimerization cofactor of the transcription factor HNF-1α . Biochemistry. 2010 Nov 30;49(47):10187-97. doi: 10.1021/bi1015056. Epub 2010 Nov 4. PubMed PMID: 21047120.

Thompson MK, Davis MF, de Serrano V, Nicoletti FP, Howes BD, Smulevich G, Franzen S. Internal binding of halogenated phenols in dehaloperoxidase-hemoglobin inhibits peroxidase function. Biophys J. 2010 Sep 8;99(5):1586-95. doi: 10.1016/j.bpj.2010.05.041. PubMed PMID: 20816071; PubMed Central PMCID: PMC2931750.

2009

Dechene M, Wink G, Smith M, Swartz P, Mattos C. Multiple solvent crystal structures of ribonuclease A: an assessment of the method. Proteins. 2009 Sep;76(4):861-81. doi: 10.1002/prot.22393. PubMed PMID: 19291738.

Chen Z, de Serrano V, Betts L, Franzen S. Distal histidine conformational flexibility in dehaloperoxidase from Amphitrite ornata. Acta Crystallogr D Biol Crystallogr. 2009 Jan;65(Pt 1):34-40. doi: 10.1107/S0907444908036548. Epub 2008 Dec 18. PubMed PMID: 19153464.

Walters J, Pop C, Scott FL, Drag M, Swartz P, Mattos C, Salvesen GS, Clark AC. A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis. Biochem J. 2009 Dec 10;424(3):335-45. doi: 10.1042/BJ20090825. PubMed PMID: 19788411; PubMed Central PMCID: PMC2805924.

2008

Longo A, Guanga GP, Rose RB. Crystal structure of E47-NeuroD1/beta2 bHLH domain-DNA complex: heterodimer selectivity and DNA recognition. Biochemistry. 2008 Jan 8;47(1):218-29. Epub 2007 Dec 11. PubMed PMID: 18069799.